There are some normal medical conditions that you hear of in your everyday life. You even come across people suffering from them daily like diabetes, hypertension, arthritis. But some rare medical conditions are quite rare and you don’t come across them daily. When you first hear about it, it is quite hard to believe that something like this exists. However, how many of these conditions seem weird but they happen to few people across the globe.


 FOREIGN ACCENT SYNDROME -Rare medical disorder

One of the very rare medical conditions with only 60 registered cases. In this unique condition, a patient speaks in an accent different from a native accent as the name also suggests. This speech hindrance may be the result of a neurological condition, mental health condition, stroke or traumatic brain injury (neuroglial damage). It is not a true accent change but a perception of the listener as a foreign accent. Many researchers found that recorded episodes of accent changes from American English to British English, Japanese to Korean, British English to French, and from Spanish to Hungarian. It is more prominent in women than men aged between 25 to 49 years of age.

Speech therapy may help to overcome this but the symptoms can last for years or even become permanent.


Auto Brewery syndrome or gut fermentation is one of the rare medical conditions in which a fungus, yeast in the gut, rapidly converts carbohydrates into alcohol. People experience drunkenness without consuming alcohol at all. As you know, our gastrointestinal tract is home to many microorganisms and out of which, bacteria form the majority while fungi account for only less than 0.1% of microbes present inside the average human gut. A type of yeast, Candida is the most commonly found fungal species in the human gut. Auto- Brewery syndrome is the result of microbiome imbalance and gastrointestinal disease.


You might have binge-watched The Vampire Diaries, The Originals, etc. In this series, you might have come across the term werewolf. There is a syndrome in which patients suffering from this are characterized by excessive hair growth on a person’s body. It is also known as hypertrichosis which can affect both male and female but this happens quite rare due to genetic mutation. Abnormal hair growth occurs on some patches or whole bodies. This condition has no cure.


You might have heard about Sleeping beauty in your fairy tale fantasy but have you heard of the syndrome named on this? Sleeping beauty syndrome also known as Kleine- Levin syndrome (KLS) is a rare disorder characterized by recurring periods of excessive sleepiness, about 20 hours a day, hence the name. Interestingly, 70% to 90% of the affected individuals are male and this usually affects teenagers but can even be present in adults or children too. These episodes can even trigger other symptoms like hallucinations, disorientation, excessive sex drive, irritability, increased appetite and childish behaviour. Its prevalence is about 1 case per million people. A study reported that about ten per cent of affected people were suffering from some neurological condition before the appearance of KLS. 


Trichotillomania, also known as pathological hair pulling is an underdiagnosed psychological disorder. People with this disorder experience an urge to pull out their hair and this urge often leads to hair loss. It is thought to be a subcategory of OCD. According to the National Organization of Rare Diseases (NORD), the patches of baldness of eyebrows, eyelashes, beard and hair caused due to pulling, can cause emotional distress in individuals affected.


During the harsh winter season, everyone assumes they are allergic to cold but some people are. This condition seems quite unreal but this exists. This is known as Familial cold autoinflammatory syndrome. It is a medical condition in which a patient suffers from episodes of fever, joint pain, blurred vision, nausea from exposure to cold temperature and skin rash. These episodes commonly occur during the early stages of life that is infancy and throughout life. People with this condition generally show symptoms after a few minutes to hours of getting exposed to cold. According to the National Organization of Rare Disease (NORD), these episodes last on an average of 12 hours but may continue to almost 3 days. Swelling may occur in extreme cases. The familial cold autoinflammatory syndrome is quite a rare condition and is believed to have a prevalence of less than 1 per million people.


Water allergy, also known as Aquagenic Urticaria is one of the rare forms of Urticaria, it is a type that causes a rash that appears after touching the water. Once the water is gone, the rash disappears within 30 to 60 minutes. According to the Genetic and Rare Disease information centre (GARD), a water test is run to diagnose this condition. Hives from this condition can be triggered by any water resources including rain, snow and even sweat and tears. There is no cure but treatment is available as the use of antihistamines, ultraviolet light therapy, and injectable medication. Aquagenic Urticaria affects around one among every 230 million people.